Empowering patients. Enriching lives.
CLEARUM™ HS DIALYZERS

The membrane
that matters:

Safe1, Effective1, Green2-4
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Clearum™ high flux Steam Sterilized (HS) Dialyzers are standard hemodialysis dialyzers, biocompatible, and provide adequate balance between diffusion and convection in HD, HF and HDF1,5,6.

Demonstrated usability among machines on the market7.

Safe

BPA Free8
avoids additional protein-bound toxins difficult to filter9

Steam Sterilized

improves hemocompatibility10‑13

Effective

Effective blood purification

without critical protein loss1, 5, 6

Based on the
Sieving Coefficient

retains essential nutrients and proteins1, 5, 6

Green

Made of Polypropylene14
reduces carbon footprint by 60%2

Steam Sterilized

avoids releasing ozone material into the environment4

Performance Information5,6,13*

IN VITRO CLEARANCE & ULTRAFILTRATION (UF) COEFFICIENT

a In vitro clearance: QB – 300 mL/min, QF – 10 mL/min, QD – 500 mL/min
b UF coefficient: QB – 300 mL/min, bovine blood Hct – 32 ± 3 %, protein – 60 ± 5 g/l

ULTRA FILTRATION RATE
c UF coefficient: QB – 300 ml/min, bovine blood Hct – 32 ± 3 %, protein – 60 ± 5 g/l
SIEVING COEFFICIENT
d Experimental values according to IFU

Ordering Information

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References

  1. Maduell F, Broseta JJ, Guillen MA, et al. Efficacy and Safety of the Clearum Dialyzer. Artif Organs. 2021;45(10):1195-1201.
  2. Keoleian G, Miller S, De Kleine R, Fang A, Mosley J. Life Cycle Material Data Update for GREET Model. University of Michigan: Ann Arbor. 2012:1-74
  3. Efficiency of recovery for solvent and water in CLEARUM GmbH, (Sept 2nd-2019)
  4. GIPA-IIA, 2017, A comparison of gamma, e-beam, x-ray and ethylene oxide technologies for the industrial sterilization of medical devices and healthcare product
  5. TR_SIE_007_R02_Clearum Sieving Coefficient Test Report
  6. TR_CLE_008_R02_Clearum Clearance Test Report
  7. Clearum™ HS Series LCDReport_Rev00
  1. INR.086_R00 – BPA Absence evaluation
  2. Krieter DH, Canaud B, Lemke HD, et al. Bisphenol A in chronic kidney disease. Artif Organs. 2013;37(3):283-90.
  3. Müller TF, Seitz M, Eckle I, et al. Biocompatibility Differences with Respect to the Dialyzer Sterilization Method. Nephron. 1998;78(2):139-142
  4. De S, Roy A. Hemodialysis Membranes:For Engineers to Medical Practitioners (1st Ed.). 2017. CRC Press
  5. Allard B, Bergi R, Potier J, Coupel S. Dialyzers biocompatibility and efficiency determinants of sterilization method choice. Pharmacien Hospitalier et Clinicie. 2013;48(4):294-255
  6. TR_UFR_008_R01_Clearum Ultrafiltration Rate Test Report
  7. TR_SUW_003_R00_Clearum Shipping Unit Weight Test Report

* The measurements in the charts above are taken in accordance with EN ISO 8637-1. The values indicated are to be considered approximate and may vary due to measurement methods, inherent variations of the membrane, manufacturing and storage conditions. During the treatment, performance on the individual patient may vary due to variable clinical parameters of the patient.


EMEA-RC-2300036