Flexya Hemodialysis System
Addressing diversity among dialysis patients is a key challenge. The Flexya hemodialysis system goes beyond standard hemodialysis. Real-time monitoring with biofeedback and advanced therapies, powered by Flexya, deliver customizable treatments to match your patients’ needs.
Designed for therapies. Powered by you.
Flexya offers the following treatment modes:
- Hemodialysis (HD)
- Hemofiltration (HF)
- Hemodiafiltration (HDF)
- Hemodiafiltration with endogenous reinfusion (HFR)
Available in single or double vascular access mode.
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Discover our membrane offering
From routine dialysis to advanced treatments for complex patients.
Advanced therapies
The next generation of hemodiafiltration.
Designed to replicate a healthy kidney
Hemodiafiltration with endogenous reinfusion (Supra HFR) is an advanced alternative to hemodiafiltration online for patients with several comorbidities, aiming at:
- Meaningful removal of large molecular weight and protein-bound toxins1,2
- Beneficial molecules preservation5
- Improvement of inflammatory conditions1,2,4
Supra HFR marks a significant step in the evolution of hemodialysis for a variety of patients, especially those with inflammation,1,2,4 autoimmune disease,3 and poor nutritional status.5
Personalized hemodynamic balance
Supra HFR Aequilibrium is Supra HFR with the addition of the Natrium sensor, which provides osmotic balance biofeedback. This solution benefits dialysis patients with comorbidities such as:
- Cardiovascular instability6,7
- Sodium imbalance6,7
Automatica™ BL500 bloodlines
Automatica™ BL500 bloodlines help streamline setup for dialysis treatments:
- Improved automation includes cassette positioning, pump segment loading, “one-button” priming, and the air removal procedure
- The use of Automatica™ BL500 bloodlines reduces the number of set-up steps needed to prepare the machine up to 40 percent (compared to standard hemodialysis systems)8
Liquid hemodialysis concentrates
We offer the following options:
- LYMPHA™ – Acetate-free liquid hemodialysis concentrate with glucose
- ACIDFLEX – Liquid hemodialysis acid concentrate with glucose
Additional resources
Products may not be available in all countries. If you have a question regarding product availability, please email us or complete this form.
Flexya Hemodialysis System is an active, non-invasive, class IIb medical device, CE0123, manufactured by Bellco S.r.l.
Automatica™ BL500 bloodlines, LYMPHA™ acetate-free solutions, ACIDFLEX solutions, Clearum™ HS, Phylther™, OLpūr™* and Supra dialysers, Biflexy™ Sodium bicarbonate bag, Bidry and Solucart sodium bicarbonate cartridges, Selecta and Suprasorb adsorbent resin cartridges are non-active, non-invasive, class IIb medical devices, CE0123, manufactured by Bellco S.r.l.
SNsp accessory for Flexya, H2Oclean™ and Dialyclean™ ultrafilters are non-active, non-invasive, class IIa medical devices, CE0123, manufactured by Bellco S.r.l.
Supra HFR and Supra HFR Aequilibrium are therapies delivered through the BL650 KITs for Flexya that are classified as procedure packs according to Art. 22 of EU MDR 2017/745.
Please refer to the devices and procedure pack Instructions for Use for complete instructions, contraindications, warnings and precautions.
OLpūr™* is a trademark of Nephros, used under license.
- Riccio E, Cataldi M, Minco M, et al. Evidence that pcresol and IL-6 are adsorbed by the HFR cartridge: towards a new strategy to decrease systemic inflammation in dialyzed patients? PLoS One. 2014;9(4):e95811.
- Esquivias-Motta E, Martín-Malo A, Buendia P, et al. Hemodiafiltration with endogenous reinfusion improved microinflammation and endothelial damage compared with online-hemodiafiltration: a hypothesis generating study. Artif Organs. 2017;41(1):88-98.
- Solano FG, Bellei E, Cuoghi A, Caiazzo M, Bruni F. Radical improvement of signs and symptoms in systemic lupus erythematosus when treated with hemodiafiltration with endogenous reinfusion dialysis. Case Rep Nephrol Dial. 2015;5(1):106-112.
- Borrelli S, Minutolo R, De Nicola L, et al. Effect of hemodiafiltration with endogenous reinfusion on overt idiopathic chronic inflammation in maintenance hemodialysis patients: a multicenter longitudinal study. Hemodial Int. 2014;18(4):758-766.
- Palleschi S, Ghezzi PM, Palladino G, et al. Vitamins (A, C and E) and oxidative status of hemodialysis patients treated with HFR and HFR-Supra. BMC Nephrol. 2016;17(1):120.
- Livon M, Apuzzo D, Bari F, et al. Efficacy And Safety of Supra HFR Aequilibrium. G Ital Nefrol. 2022;S79(39):137-138.
- Donati G, Ursino M, Spazzoli A, et al. Sodium prescription in the prevention of intradialytic hypotension: new insights into an old concept. Blood Purif. 2018;45(1-3):61-70.
- Based on internal test report, Flexya vs. Formula™ Therapy: comparative assessment of the level of automation. 2020 July.
