CHRONIC HEMODIALYSIS SYSTEMS

Flexya Hemodialysis System

Addressing diversity among dialysis patients is a key challenge. The Flexya hemodialysis system goes beyond standard hemodialysis. Real-time monitoring with biofeedback and advanced therapies, powered by Flexya, deliver customizable treatments to match your patients’ needs.

Designed for therapies. Powered by you.

Flexible treatments to meet the therapeutic needs of your Chronic Kidney Disease patients.

Flexya offers the following treatment modes:

  • Hemodialysis (HD)
  • Hemofiltration (HF)
  • Hemodiafiltration (HDF)
  • Hemodiafiltration with endogenous reinfusion (HFR)

Available in single or double vascular access mode.

Explore more about Flexya

Discover our membrane offering

From routine dialysis to advanced treatments for complex patients.

Advanced therapies

The next generation of hemodiafiltration.

Designed to replicate a healthy kidney

Hemodiafiltration with endogenous reinfusion (Supra HFR) is an advanced alternative to hemodiafiltration online for patients with several comorbidities, aiming at:

  • Meaningful removal of large molecular weight and protein-bound toxins1,2
  • Beneficial molecules preservation5
  • Improvement of inflammatory conditions1,2,4

Supra HFR marks a significant step in the evolution of hemodialysis for a variety of patients, especially those with inflammation,1,2,4 autoimmune disease,3 and poor nutritional status.5

Personalized hemodynamic balance

Supra HFR Aequilibrium is Supra HFR with the addition of the Natrium sensor, which provides osmotic balance biofeedback. This solution benefits dialysis patients with comorbidities such as:

  • Cardiovascular instability6,7
  • Sodium imbalance6,7

Automatica BL500 bloodlines

Extracorporeal circulation devices for use with the Flexya machine

Automatica™ BL500 bloodlines help streamline setup for dialysis treatments:

  • Improved automation includes cassette positioning, pump segment loading, “one-button” priming, and the air removal procedure
  • The use of Automatica™ BL500 bloodlines reduces the number of set-up steps needed to prepare the machine up to 40 percent (compared to standard hemodialysis systems)8

Liquid hemodialysis concentrates

Compatible with our machines and others available on the market

We offer the following options:

  • LYMPHA™ – Acetate-free liquid hemodialysis concentrate with glucose
  • ACIDFLEX – Liquid hemodialysis acid concentrate with glucose

Products may not be available in all countries. If you have a question regarding product availability, please email us or complete this form.

Flexya Hemodialysis System is an active, non-invasive, class IIb medical device, CE0123, manufactured by Bellco S.r.l.

Automatica™ BL500 bloodlines, LYMPHA™ acetate-free solutions, ACIDFLEX solutions, Clearum™ HS, Phylther™, OLpūr™* and Supra dialysers, Biflexy™ Sodium bicarbonate bag, Bidry and Solucart sodium bicarbonate cartridges, Selecta and Suprasorb adsorbent resin cartridges are non-active, non-invasive, class IIb medical devices, CE0123, manufactured by Bellco S.r.l.

SNsp accessory for Flexya, H2Oclean™ and Dialyclean™ ultrafilters are non-active, non-invasive, class IIa medical devices, CE0123, manufactured by Bellco S.r.l.

Supra HFR and Supra HFR Aequilibrium are therapies delivered through the BL650 KITs for Flexya that are classified as procedure packs according to Art. 22 of EU MDR 2017/745.

Please refer to the devices and procedure pack Instructions for Use for complete instructions, contraindications, warnings and precautions.

OLpūr™* is a trademark of Nephros, used under license.

  1. Riccio E, Cataldi M, Minco M, et al. Evidence that pcresol and IL-6 are adsorbed by the HFR cartridge: towards a new strategy to decrease systemic inflammation in dialyzed patients? PLoS One. 2014;9(4):e95811.
  2. Esquivias-Motta E, Martín-Malo A, Buendia P, et al. Hemodiafiltration with endogenous reinfusion improved microinflammation and endothelial damage compared with online-hemodiafiltration: a hypothesis generating study. Artif Organs. 2017;41(1):88-98.
  3. Solano FG, Bellei E, Cuoghi A, Caiazzo M, Bruni F. Radical improvement of signs and symptoms in systemic lupus erythematosus when treated with hemodiafiltration with endogenous reinfusion dialysis. Case Rep Nephrol Dial. 2015;5(1):106-112.
  4. Borrelli S, Minutolo R, De Nicola L, et al. Effect of hemodiafiltration with endogenous reinfusion on overt idiopathic chronic inflammation in maintenance hemodialysis patients: a multicenter longitudinal study. Hemodial Int. 2014;18(4):758-766.
  5. Palleschi S, Ghezzi PM, Palladino G, et al. Vitamins (A, C and E) and oxidative status of hemodialysis patients treated with HFR and HFR-Supra. BMC Nephrol. 2016;17(1):120.
  6. Livon M, Apuzzo D, Bari F, et al. Efficacy And Safety of Supra HFR Aequilibrium. G Ital Nefrol. 2022;S79(39):137-138.
  7. Donati G, Ursino M, Spazzoli A, et al. Sodium prescription in the prevention of intradialytic hypotension: new insights into an old concept. Blood Purif. 2018;45(1-3):61-70.
  8. Based on internal test report, Flexya vs. Formula™ Therapy: comparative assessment of the level of automation. 2020 July.

Order Information

Flexya equipment
Order code
Description
Unit of measure
Quantity
IBN03X701
Flexya machine: 220-240V / for Biflexy™ bicarbonate powder bag
Each
1
IBN03X301
Flexya machine: 110-120V / for Biflexy™ bicarbonate powder bag
Each
1
IBN03X700
Flexya machine: 220-240V / for Bidry bicarbonate cartridge for haemodialysis
Each
1
IBN03X300
Flexya machine: 110-120V / for Bidry bicarbonate cartridge for haemodialysis
Each
1
Flexya consumables
Order code
Description
Unit of measure
Quantity
IBP4313
H2Oclean™ incoming water ultrafilter for Flexya machine
Box
6
IBP4314
Dialyclean™ dialysis fluid ultrafilter for Flexya machine
Box
6
IB0700000
Biflexy™ 750 g bicarbonate powder bag
Box
8
IB0700001
Biflexy™ 900 g bicarbonate powder bag
Box
6
IB0700002
Biflexy™ 1300 g bicarbonate powder bag
Box
5
BSCART003
Bidry 750 g bicarbonate cartridge for haemodialysis
Box
12
BSCART009
Bidry 950 g bicarbonate cartridge for haemodialysis
Box
12
BSCART002
Solucart Plus 750 g bicarbonate cartridge for haemodialysis
Box
10
BSCART018
Solucart Plus 850 g bicarbonate cartridge for haemodialysis
Box
10
IBP1503
Selecta cartridge for ultrafiltrate regeneration
Box
20
IBP1560
Suprasorb cartridge for ultrafiltrate regeneration
Box
20
BHD0000N
Automatica™ BL500 bloodline for bicarbonate hemodialysis
Box
18
BHD0010N
Automatica™ BL500 bloodline for single-needle bicarbonate hemodialysis
Box
14
BHD1000N
Automatica™ BL500 bloodline for bicarbonate hemodialysis with Hemox
Box
18
HDF0000N
Automatica™ BL500 bloodline for online hemodiafiltration in pre, post, pre + post dilution
Box
16
HDF1000N
Automatica™ BL500 bloodline for online hemodiafiltration with Hemox in pre, post, pre + post dilution
Box
16
HFR0000N
Automatica™ BL500 bloodline for HFR therapy
Box
14
HFR0100N
Automatica™ BL500 bloodline for HFR therapy with Natrium
Box
14
HFR1000N
Automatica™ BL500 bloodline for HFR therapy with Hemox
Box
14
HFR1100N
Automatica™ BL500 bloodline for HFR therapy with Hemox and Natrium
Box
14
MID0000N
Automatica™ BL500 bloodline for Mid-dilution therapy
Box
16
MID1000N
Automatica™ BL500 bloodline for Mid-dilution therapy with Hemox
Box
16
IB0577120/F
Expansion chamber for single-needle, single-pump (SNsp) haemodialysis treatment (only with Automatica™ BL500 BHD and HDF bloodlines)
Box
20
†Single-needle, double-pump treatment mode.
Dialyzers and advanced therapies
Order code
Description
Unit of measure
Quantity
IBP4370
Clearum™ HS Dialyzer - 1,3 m2 High Flux Dialyzer, steam sterilized
Box
21
IBP4371
Clearum™ HS Dialyzer - 1,5 m2 High Flux Dialyzer, steam sterilized
Box
21
IBP4372
Clearum™ HS Dialyzer - 1,7 m2 High Flux Dialyzer, steam sterilized
Box
21
IBP4373
Clearum™ HS Dialyzer - 2,0 m2 High Flux Dialyzer, steam sterilized
Box
18
IBP4374
Clearum™ HS Dialyzer - 2,2 m2 High Flux Dialyzer, steam sterilized
Box
18
IBP4240/UP
Phylther™ UP Dialyzer - 1,3 m2 High Flux Dialyzer, steam sterilized
Box
21
IBP4242/UP
Phylther™ UP Dialyzer - 1,5 m2 High Flux Dialyzer, steam sterilized
Box
21
IBP4244/UP
Phylther™ UP Dialyzer - 1,7 m2 High Flux Dialyzer, steam sterilized
Box
21
IBP4248/UP
Phylther™ UP Dialyzer - 2,0 m2 High Flux Dialyzer, steam sterilized
Box
18
IBP4249/UP
Phylther™ UP Dialyzer - 2,2 m2 High Flux Dialyzer, steam sterilized
Box
18
IB0958105
OLpūr™* - 2,2 m2 hemodialyzer for Mid-Dilution hemodiafiltration
Box
36
IB0569215
Mid-dilution 220 Hemox kit : MID1000N Automatica™ bloodlines + IB0958105 OLpūr™* 2,2 m2 hemodialyzer
Box
12
IBP4300
Supra dual-chamber hemodiafiltration device with 0.7 m2 hemofilter and 1.3 m2 dialyzer
Box
20
IBP4301
Supra dual-chamber hemodiafiltration device with 0.7 m2 hemofilter and 1.7 m2 dialyzer
Box
20
IB0569208
BL650 KIT Supra13 Flexya: IBP4300 Supra13 double chamber filter + IBP1560S Suprasorb adsorbent cartridge + HFR0000 Automatica™ BL500 bloodline for HFR
Box
1
IB0569209
BL650 KIT Supra17 Flexya: IBP4301 Supra17 double chamber filter + IBP1560S Suprasorb adsorbent cartridge + HFR0000 Automatica™ BL500 bloodline for HFR
Box
1
IB0569210
BL650 KIT Supra13 HEM.Flexya: IBP4300 Supra13 double chamber filter + IBP1560S Suprasorb adsorbent cartridge + HFR1000 Automatica™ BL500 bloodline for HFR with Hemox
Box
1
IB0569211
BL650 KIT Supra17 HEM.Flexya: IBP4301 Supra17 double chamber filter + IBP1560S Suprasorb adsorbent cartridge + HFR1000 Automatica™ BL500 bloodline for HFR with Hemox
Box
1
IB0569222
BL650 KIT Supra13 AEQ. Flexya: IBP4300 Supra13 double chamber filter + IBP1560S Suprasorb adsorbent cartridge + HFR0100 Automatica™ BL500 bloodline for HFR with Natrium
Box
1
IB0569223
BL650 KIT Supra17 AEQ. Flexya: IBP4301 Supra17 double chamber filter + IBP1560S Suprasorb adsorbent cartridge + HFR0100 Automatica™ BL500 bloodline for HFR with Natrium
Box
1
IB0569224
BL650 KIT Supra13 AEQ. HEM.Flexya: IBP4300 Supra13 double chamber filter + IBP1560S Suprasorb adsorbent cartridge + HFR1100 Automatica™ BL500 bloodline for HFR with Natrium and Hemox
Box
1
IB0569225
BL650 KIT Supra17 AEQ. HEM.Flexya: IBP4301 Supra17 double chamber filter + IBP1560S Suprasorb adsorbent cartridge + HFR1100 Automatica™ BL500 bloodline for HFR with Natrium and Hemox
Box
1
OLpūr™* is a trademark of Nephros, used under license.